436例支原体培养阳性病例药敏结果分析

Positive mycoplasma cultivation and its susceptibility to antibiotics—analysis of 436 cases

目的:观察我院436例泌尿生殖系感染支原体阳性病例抗生素的敏感性,为临床提供最新的流行病学资料及合理用药的科学依据。方法:采用支原体药敏混合试剂对泌尿生殖系感染患者进行支原体培养和药敏试验。结果:本组436支原体培养阳性,其中解脲支原体(Uu)单纯感染占72.48%,人型支原体(Mh)单纯感染占4.13%,解脲支原体(Uu)与人型支原体(Mh)混合感染占23.39%。支原体对12种抗菌药物最敏感为交沙霉素、美满霉素、强力霉素,总耐药率最高是环丙沙星。结论:非淋菌性泌尿生殖系统支原体感染主要以Uu发病率最高,可首选交沙霉素、美满霉素和强力霉素治疗。

Objective：To observe the susceptibilities to antibiotics of 436patients infected with posi-tive mycoplasma in uroreproductive tract so as to provide clinical up-to-date epidemiological data and scientific basis in rational drug uses.Methods：Mycoplasma susceptibility test kit was applied to conducting mycoplasma cultivation and drug susceptibility test on uroreproductive tract infec-tors.Results：Of the 436patients,72.48% were infected with ureaplasma urealyticum（UU）,4.13% with Mycoplasma hominis（Mh）and 23.3%were mixed infected with UU and Mh.Among the 12kinds of antibiotics,the most susceptible one on mycoplasma were Josamycin,Minocycline and Doxycycline,the highest of the total drug-resistance rate was Ciprofloxacin.Conclusion：The highest mycoplasma infection rate in non-gonococcal urogenital tract is Uu infection,so the first choice of drugs in treatment are Josamycin,Minocycline and Doxycycline.