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超高效液相色谱(UPLC)在药物代谢动力学中的应用 被引量：2

Recent Application of Ultra High Performance Liquid Chromatography in Pharmacokinetics
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摘要 目的介绍超高效液相色谱(UPLC)的发展、理论基础、在药物代谢动力学中的应用及展望。方法总结了UPLC具有能缩短分析时间和减少溶剂消耗等诸多优势及在药物代谢动力学上的应用。结果与结论UPLC是一种柱效高、发展前景好的液相色谱技术,在药物代谢动力学领域有广泛的应用前景。 Objective To introduce foundation and development,theory and application in pharmacokinetics of ultra performance liquid chromatography（UPLC）.Methods Summarize advantages with decrease of analysis time and solvent consumption,as well as application of UPLC in pharmacokinetics.Results and Conclusion UPLC is a liquid chromatography technology with high column efficiency and good prospect,and could be widely used in pharmacokinetics.
作者 朱凌 张双庆 李佐刚
机构地区 中国食品药品检定研究院国家药物安全评价监测中心
出处 《中国药事》 CAS 2011年第8期829-831,共3页 Chinese Pharmaceutical Affairs
关键词 UPLC HPLC 药代动力学 UPLC HPLC pharmacokinetics
分类号 R917 [医药卫生—药物分析学] R969.1 [医药卫生—药理学]
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参考文献12

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中国药事
2011年 第8期

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