D-二聚体对骨折并发深静脉血栓的早期诊断价值

Early diagnostic value of D-dimer for deep vein thrombosis after fracture

目的探讨骨折并发下肢深静脉血栓(DVT)患者D-二聚体(DD)定量测定的临床价值。方法采用免疫比浊法对160例骨折并发下肢深静脉血栓患者术前、术后3 d、术后7 d进行DD的定量检测,并随访患者的病情。结果 160例患者有20例并发DVT,并发DVT组术前、术后3 d、术后7 d DD检测结果比较差异有统计学意义(P<0.05);未并发DVT组术前、术后3 d、术后7 d DD检测结果比较差异无统计学意义(P>0.05)。并发DVT组与未并发DVT组相比,术前DD的检测结果比较差异无统计学意义(P>0.05)。术后3 d及7 d的DD检测结果比较差异有统计学意义(P<0.05)。结论 DD的动态监测对骨折并发DVT具有早期诊断价值。

Objective To investigate the early diagnostic value of D-dimer assay for deep vein thrombosis（DVT） after fracture.Methods Quantitively detect D-dimer in 160 patients with fracture during the phases preoperative,3 days postoperative,7 days postoperative by immunity-turbidity method,and follow up the patients＇ conditions.Results Twenty patients occured deep vein thrombosis.The different levels of D-dimer during the phases preoperative,3 days postoperative and 7 days postoperative in DVT group was significant（P0.05）.The different levels of D-dimer during the phases preoperative,3 days postoperative and 7 days postoperative in one DVT group was not significant（P0.05）.The different level of D-dimer between the two groups： preoperative was not significant（P0.05）,3 days postoperative and 7 days postoperative was significant（P0.05）.Conclusion Dynamic deter mination of D-dimer has early diagnostic value for fracture complicated with DVT.