外周性原始神经外胚层肿瘤的CT影像学诊断分析

Diagnostic analysis of CT for peripheral perimitive neuroectodermal tumors

目的探讨外周性原始神经外胚层瘤(pPNET)的影像学表现,以提高对本病的认识。方法搜集暨南大学第四附属医院经病理证实的pPNET 6例,行CT平扫及增强扫描,分析其影像学表现特点。结果 3例病灶位于胸腔,1例位于颈胸部,1例位于髂骨,1例位于大腿。CT显示大部分病例主要表现为边界清的软组织肿块,密度不均匀伴坏死、囊变,极少钙化,增强后明显不均匀强化。发生于骨的PNET CT表现为溶骨性骨质破坏并软组织肿块形成。结论外周性PNET的CT表现缺乏特异性影像学特征;CT检查可显示肿瘤的内部结构,明确肿瘤的范围和发现远处转移。

Objective To investigate the imaging diagnostic value of peripheral primitive neuroectodermal tumors（pPNET） and to improve the recognition of it. Methods Six cases of pPNET proved by clinic pathology collected in the study.Six cases had undergone CT scanning with contrast enhancement of 4 cases.The imaging characteristics were retrospectively analyzed.Results The tumors were located in the chest（3 cases）,neck and chest（one case）,ilium（one case） and thigh（one case）.The majority of tumors showed a large,clear-defined,non-calcified mass and heterogeneous appearance with hypodense cystic areas.The tumors demonstrated heterogeneous contrast enhancement.The pPNET arising in bone demonstrated extensive lytic lesion with soft tissue mass.Conclusion The study of radiology on pPNET does not show specificity.CT findings on pPNET can provide more information of its internal structure,involved area.CT can also be useful in detection of distant metastasis.