摘要
Treatment of chiral N-tert-butyl sulfinylimines with ethyl bromofluoroacetate in the presence of activated Zn dust in THF afforded the α-fluoro- β-amino acid derivatives in good yields（70-86%） and moderate diastereoselectivity（66：34-92：8）.
Treatment of chiral N-tert-butyl sulfinylimines with ethyl bromofluoroacetate in the presence of activated Zn dust in THF afforded the α-fluoro- β-amino acid derivatives in good yields（70-86%） and moderate diastereoselectivity（66：34-92：8）.
基金
The Shanghai Pujiang Program(No.09PJ 1400800)
the Fundamental Research Funds for the Central Universities are greatly acknowledged for funding this work
