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动态血糖监测系统对HbA1c<6.5%的2型糖尿病患者无症状低血糖事件的评估价值 被引量:12

Clinical significance of the continuous glucose monitoring on asymptomatic hypoglycaemia reaction in type 2 diabetes mellitus patients with HbA1c<6.5%
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摘要 目的:评价动态血糖监测系统(CGMS)对糖化血红蛋白(HbA1c)<6.5%的2型糖尿病(T2DM)患者胰岛素治疗中无症状低血糖事件的重要意义。方法:将87例使用胰岛素治疗的HbA1c<6.5%的T2DM患者随机分成CGMS组和自我血糖监测(SMBG)组。CGMS组进行连续72 h血糖监测,SMBG组每天监测8次毛细血糖,共3 d。比较两种监测方法对低血糖,尤其是无症状低血糖的检出率。结果:SMBG组患者监测3 d发现12例出现16次低血糖,其中4例无症状低血糖5次;CGMS监测72 h发现29例出现108次低血糖,其中23例无症状低血糖65次,以夜间多见,66.7%见于病程超过10年的患者。结论:CGMS在HbA1c<6.5%的T2DM患者胰岛素治疗中可作为监测低血糖尤其是无症状低血糖的较好方法。 Objective:To evaluate the continuous glucose monitoring on hypoglycaemia reaction in type 2 diabetes mellitus patients(T2DM) with HbAlc 〈 6.5%. Methods: Eighty-seven patients of T2DM with HbAle 〈 6.5% undergoing insulin intensification therapy were randomly divided into continuous glucose monitoring system(CGMS) group and self-monitoring of blood glucose (SMBG) group. The blood glucose levels of the CGMS group were monitored continuously using CGMS for 72 hours. The blood glucose levels of the SMBG group were monitored using finger tip blood glucose meters eight times a day for three days. Hypoglycemia, especially asymptomatie hypoglycemia's detection rate was compared between two groups. Results:Twelve patients had hypoglycemia( 16 times) and 4 of them had asymptomatic hypoglycemia (5 times ) in SMBG group during three days. While 29 patients had hypoglycemia( 108 times) and 23 of them had asymptomatic hypght and more common in course of m^re than l0 years of patients. Conclusion:CGMS is a better metoglycemia(65 times) in CGMS group during 72 hours. Hypoglycemia is found more frequently in the nihod on detecting hypoglycemia, especially asymptomatic hypoglycemia in T2DM patients treated with insufin intensification therapy.
出处 《现代医学》 2011年第4期406-408,共3页 Modern Medical Journal
关键词 2型糖尿病 动态血糖监测系统 自我血糖监测 无症状低血糖 type 2 diabetes mellitus continuous glucose monitoring system self-monitoring of blood glucose asymptomatic hypoglycemia
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参考文献10

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二级参考文献25

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