亚低温治疗重型颅脑损伤的临床研究

The clinical study of hypothermia treatment of severe craniocerebral injury

目的探讨亚低温脑保护疗法对救治重型颅脑损伤的疗效。方法将132例重型颅脑损伤随机平均分为治疗组与对照组,进行对比分析,并且前瞻性分析两组疗效。结果治疗组66例患者,存活率为77.3%,恢复良好率54.5%(36/66),病死率18.2%(12/66)。疗效明显优于对照组,未发生相关的并发症。结论亚低温治疗能显著降低重型颅脑损伤患者的死亡率,改善颅脑损伤患者神经功能预后,并具有安全、显著降低病死率及癫痫发生率等优点。

Objective To study the brain protection of mild hypothermia therapy on the efficacy of treatment of severe head injury.Methods 132 patients with severe traumatic brain injury were randomly divided into treatment group and control group were analyzed,and prospective analysis of two groups.66 patients treated group,the survival rate was 77.3%,good recovery rate of 54.5%（36/66）,mortality rate was 18.2%（12/66）.The effect was better intreatment group than the control group,without any related complications.Conclusion Mild hypothermia can significantly reduce mortality in patients with severe traumatic brain injury and improve neurological outcome in patients with traumatic brain injury and is safe and significantly reduce the mortality and incidence of epilepsy and other advantages.