期刊文献+

免疫抑制在预防1型糖尿病发病中的作用 被引量:7

下载PDF
导出
摘要 近年来,糖尿病患病率呈急剧上升趋势,IDF(国际糖尿病联盟)2010年报告指出全球糖尿病患者已达2.46亿。预计到2025年糖尿病患者增至3.88亿。我国糖尿病患者已接近9240万,其中2型糖尿病占90%~95%,1型糖尿病的患病率也以2%~5%的速度增长。
出处 《中国免疫学杂志》 CAS CSCD 北大核心 2011年第8期760-762,共3页 Chinese Journal of Immunology
基金 国家自然科学基金(30772042) 国家973前期专项(2007CB516811) 深圳市科技计划项目(201001005)资助
  • 相关文献

参考文献33

  • 1Simmons R K,Unwin N,Griffin S J.International Diabetes Federation:An update of the evidence concerning the prevention of type 2 diabetes[J].Diabetes Res Clin Pract,2010;87(2):143-149.
  • 2Daneman D.State of the world's children with diabetes[J].Pediatric Diabetes,2009;10(2):120-126.
  • 3Atkinson M A,Eisenbarth G S.Type 1 diabetes:new perspectives on disease pathogenesis and treatment[J].Lancet,2001;358(9277):221-229.
  • 4Staeva-Vieira T,Peakman M,von Herrath M.Translational mini-review series on type 1 diabetes:Immune-based therapeutic approaches for type 1 diabetes[J].Clin Exp Immuno,2007;148(1):17-31.
  • 5Sobel D,Henzke A,Abbassi V.Cyclosporin and methotrexate therapy induces remission in type 1 diabetes mellitus[J].Acta Diabetologica,2010;47(3):243-250.
  • 6Chatenoud L,Bluestone J A.CD3-specific antibodies:a portal to the treatment of autoimmunity[J].Nature Reviews Immunology,2007;7(8):622-632.
  • 7Rewers M,Gottlieb P.Immunotherapy for the pevention and treatment of type 1 diabetes human trials and a look into the future[J].Diabetes Care,2009;32(10):1769-1782.
  • 8Sherry N A,Chen W,Kushner J A et al.Exendin-4 improves reversal of diabetes in NOD mice treated with anti-CD3 monoclonal antibody by enhancing recovery of beta-cells[J].Endocrinology,2007;148(11):5136-5144.
  • 9Herold K C,Bluestone J A,Montag A G et al.Prevention of autoimmune diabetes with nonactivating ANTI-CD3 Monoclona-Antibody[J].Diabetes,1992;41(3):385-391.
  • 10Haller M J,Atkinson M A,Schatz D A.Efforts to prevent and halt autoimmune beta cell destruction[J].Endocrinol Metab Clin North Am,2010;39(3):527-539.

二级参考文献28

  • 1田土.骨髓间质干细胞分化为内皮细胞增加血管密度改善慢性缺血狗的心功能[J].岭南心血管病杂志,2005,11(5):371-371. 被引量:180
  • 2郭彤,王薇,张君,陈雪,李炳震,李凌松.骨髓间充质干细胞移植治疗眼表损害的初步实验研究[J].中华眼科杂志,2006,42(3):246-250. 被引量:32
  • 3田莹,邓宇斌,黄奕俊,那晓东,李艳,叶美红.骨髓间充质干细胞在CD4^+CD25^+调节性T细胞减轻大鼠移植物抗宿主反应中的作用[J].中国实验血液学杂志,2006,14(6):1210-1214. 被引量:23
  • 4中华人民共和国科学技术部.关于善待实验动物的指导性意见.2006.09-30
  • 5Lazarus HM, Koc ON, Devine SM, et al.Cotransplantation of HLA-identical sibling culture-expanded mesenchymal stem cells and hematopoietic stem cells in hematologic malignancy patients. Biol Blood Marrow Transplant. 2005;11 (5):389-398.
  • 6Lee ST, Jang JH, Cheong JW, et al.Treatment of high-risk acute myelogenous leukaemia by myeloablative chemoradiotherapy followed by co-infusion of T cell-depleted haematopoietic stem cells and culture-expanded marrow mesenchymal stem cells from a related donor with one fully mismatched human leucocyte antigen haplotype. BrJ Haematol. 2002;118(4):1128-1131.
  • 7Itakura S, Asari S, Rawson J, et al.Mesenchymal stem cells facilitate the induction of mixed hematopoietic chimerism and islet allograft tolerance without GVHD in the rat. Am J Transplant .2007;7(2):336-346.
  • 8Bianco P, Gehron Robey P. Marrow stromal stem cells. J Clin Invest. 2000; 105(12): 1663-1668.
  • 9Peister A, Mellad JA, Larson BL, et al.Adult stem cells from bone marrow (MSCs) isolated from different strains of inbred mice vary in surface epitopes, rates of proliferation, and differentiation potential. Blood. 2004;103(5):1662-1668.
  • 10Pittenger MF, Mackay AM, Beck SC, et al. Multilineage potential of adult human mesenchymal stem cells. Science .1999;284(5411 ): 143-147.

共引文献12

同被引文献55

引证文献7

二级引证文献17

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部