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直肠癌组织中usp22的表达及其临床意义 被引量:4

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摘要 目的:检测usp22在直肠癌组织中的表达,探讨其与直肠癌发生、发展的关系及临床和病理特征。方法:采用免疫组织化学法检测usp22在直肠癌组织、直肠腺瘤和正常肠组织中的表达,研究它的表达与直肠癌恶性程度的关系以及在不同组织中表达的特点。结果:在直肠癌组织中,usp22的阳性表达率以及染色强度均随分化程度的降低而呈现出上升趋势(P<0.05)。usp22在直肠癌组织中的表达明显高于正常直肠组织(P<0.05)。于直肠腺瘤中的表达率虽高于正常直肠组织和腺瘤,但差异无显著性(P>0.05)。结论:usp22对直肠癌的发生、发展起一定作用。
作者 周飞 宁晓婷
出处 《实用医学杂志》 CAS 北大核心 2011年第18期3282-3283,共2页 The Journal of Practical Medicine
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二级参考文献19

共引文献23

同被引文献86

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