期刊文献+

基于TOAST分型的急性缺血性卒中临床疗效分析 被引量:2

下载PDF
导出
摘要 目的研究急性缺血性卒中TOAST分型与临床短期预后的关系。方法收集2010年5月—2011年4月在三峡中心医院神经内科病房住院治疗的700例急性缺血性卒中患者。缺血性卒中依据TOAST标准分型,即大动脉粥样硬化型(LAA)、心源性栓塞型(CE)、小动脉闭塞型(SAO),其他明确病因型(SOE)和不明原因型(SUE)5型。应用NIHSS评分了解不同亚型患者入院时和出院时的功能状态,以出院时神经功能好转率评价其临床短期预后,分析各亚型与临床短期预后的相关性。结果缺血性脑卒中男性患者发病年龄较女性患者早(P<0.01)。脑卒中亚型:LAA 194例(27.7%),SAO 220例(31.4%),CE 70例(10.0%),SOE8例(1.1%),SUE 208例(29.7%)。其中SAO亚型所占比例最高。各亚型与临床短期预后的关系:CE型患者入院时病情危重,神经功能缺损最严重,NIHSS评分最高(20.11±1.42)分,出院时神经功能好转率显著降低(P<0.01)。SAO亚型入院时病情最轻,NIHSS评分最低(4.10±0.36)分,出院时神经功能好转率显著增高(P<0.01)。结论 SAO亚型入院时病情最轻,临床疗效及临床短期预后最好;CE亚型入院时病情最重,临床疗效及临床短期预后最差。
出处 《中西医结合心脑血管病杂志》 2011年第8期938-939,共2页 Chinese Journal of Integrative Medicine on Cardio-Cerebrovascular Disease
  • 相关文献

参考文献7

  • 1各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33022
  • 2Bendixen BH, Kappelle LJ. Classification of subtype of acute ische- mic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10 172 in acute stroke treatment[J]. Stroke, 1993,24:35 - 41.
  • 3吴丽娥,刘鸣,张月辉,赵晓玲,杨杰,谈颂,张世洪,吴波,谭燕,王清芳,王丽春,李伟.缺血性脑卒中TOAST病因分型和预后[J].中华神经科杂志,2004,37(4):292-295. 被引量:87
  • 4Amarenco P,Bogousslavsky J, Caplan LR, et al. New approach to stroke subtyping:The A - S - C - O (phenotypic) classification of stroke[J]. Cerebrovasc Dis, 2009,27 (5) : 502 - 508.
  • 5Kolominsky- Rabas PL,Weber M,Gefeller O,et al. Epidemiology of ischemic stroke subtypes according to TOAST criteria: Inci- dence, recurrence,and long- term survival in ischemic stroke sub types: A population based study[J]. Stroke, 2001,32 ( 12 ) : 2735 - 2740.
  • 6Petty GW, Brown RD, Whisnant JP, et al. Ischemic stroke sub types : A population based study of functional outcome, suvival, and recurrence[J]. Stroke, 2000,31 (5) : 1062 - 1068.
  • 7Adams H,Davis P. Baseline NIH stroke scale score strongly pre- dicts outcome after stroke:A report of the Trial of Orgl 0172 in acute stroke treatment (TOAST) [J].Neurology,1999,53(1) 126 - 131.

二级参考文献17

  • 1Adams HP Jr, Bendixen BH, Kappelle LJ, et al. Classification of subtype of acute ischemic stroke. Definitions for use in a multicenter clinical trial. TOAST. Trial of Org 10172 in Acute Stroke Treatment. Stroke, 1993, 24: 35-41.
  • 2Kristensen B, Malm J, Carlberg B, et al. Epidemiology and etiology of ischemic stroke in young adults aged 18 to 44 years in Northern Sweden. Stroke, 1997, 28: 1702-1709.
  • 3Kolominsky-Rabas PL, Weber M, Gefeller O, et al. Epidemiology of ischemic stroke subtypes according to TOAST criteria. Stroke, 2001,32: 2735-2740.
  • 4Lee BI, Nam HS, Heo JH, et al. Yonsei stroke registry: analysis of 1000 patients with acute cerebral infarction. Cerebrovasc Dis, 2001,12: 145-151.
  • 5Bamford J, Sandercock P, Dennis M, et al. Classification and natural history of clinical subtypes of cerebral infarction. Lancet,1991, 337:1521-1526.
  • 6WHO Special Report. Stroke: recommendations on stroke prevention, diagnosis and therapy. Stroke, 1989, 20:1407-1431.
  • 7Mahoney FD, Barthel DW. Functional evaluation: the Barthel Index. Md State Med J, 1965,14:61-63.
  • 8PROGRESS Collaborative Group. Randomised trial of a perindoprilbased blood-pressure-lowering regimen among 6105 individuals with previous stroke or transient ischaemic attack. Lancet, 2001,358:1033-1041.
  • 9Kunitz SC, Gross CR, Heyman A, et al. The pilot Stroke Data Bank: definition, design, and data. Stroke, 1984, 15:740-746.
  • 10Petty GW, Brown RD, Whisnant JP, et al. Ischemic stroke subtypes: a population-based study of functional outcome, survival,and recurrence. Stroke, 2000, 31:1062-1068.

共引文献33090

同被引文献28

  • 1王志宏,韩仲岩.急性缺血性脑卒中的TOAST分型标准[J].临床神经病学杂志,2007,20(5):392-392. 被引量:48
  • 2中风病诊断与疗效评定标准(试行)[J].北京中医药大学学报,1996,19(1):55-56. 被引量:5991
  • 3各类脑血管疾病诊断要点[J].中华神经科杂志,1996,29(6):379-380. 被引量:33022
  • 4张聪,高颖.《中风病辨证诊断标准》应用现状存在问题及对策[J].天津中医药,2007,24(1):12-14. 被引量:20
  • 5中华医学会神经病学分会.脑血管疾病分类和诊断要点.中华神经科杂志,1996,:379-381.
  • 6Gao S,Wang YJ,Xu AD,et al.Chinese ischemic stroke subclassification[J].Front Neurol,2011,2:6.
  • 7Redfors P,Jood K,Holmegaard L,et al.Stroke subtype predicts outcome in young and middle-aged stroke sufferers[J].Acta Neurol Scand,2012,126(5):329-335.
  • 8Markaki L,Franzen L,Caroline Talani,et al.Long-term survival of ischemic cerebrovascular disease in the acute inflammatory stroke study,a hospital-based cohort described by TOAST and ASCO[J].Cerebrovasc Dis,2013,35(3):213-219.
  • 9Michael M,Caroline AD,Orla C,et al.Stroke subtype classification to mechanism-specific and undetermined categories by TOAST,ASCO,and Causative Classification System[J].Stroke,2010,41(8):1579-1586.
  • 10Grau AJ,Weimar C,Buggle F,et al.Risk factors,outcome,and treatment in subtypes of ischemic stroke:The German Stroke Data Bank[J].Stroke,2001,32(11):2559-2566.

引证文献2

二级引证文献13

相关作者

内容加载中请稍等...

相关机构

内容加载中请稍等...

相关主题

内容加载中请稍等...

浏览历史

内容加载中请稍等...
;
使用帮助 返回顶部