联用沙丁胺醇和溴化异丙托品雾化吸入对COPD急性加重期的治疗作用

目的探讨沙丁胺醇和溴化异丙托品联合雾化吸入对慢性阻塞性肺疾病(COPD)急性加重期患者肺功能及动脉血气的影响。方法 106例COPD急性加重期患者随机分为对照组(52例)和实验组(54例)。2组均采用常规治疗,实验组加用溴化异丙托品和沙丁胺醇平静呼吸时氧气雾化吸入,每天2次。2组患者均于治疗开始前及治疗第7天后测定肺功能及动脉血气分析。结果实验组肺功能及动脉血气较治疗前均有明显改善(P<0.05)。结论联合氧气雾化吸人溴化异丙托品和沙丁胺醇对COPD急性加重期患者的肺功能及动脉血气分析有明显的改善作用。

Objective Salbutamol, bromlnated isopropyl tetramin methenamlne joint aerosol inhalation of chronic obstructive pulmonary disease （COPD） patients with acute exacerbations period lung function and arterial blood gas influence.Methods Acute exacerbations of 106 patients COPD patients were randomly divided into the control group （52 cases） and group （n=54）. Both groups using conventional treatment, group odd with brominated isopropyl tetramin methenamlne, sulbutomol calm breathing oxygen atomization sucked, 2 times daily. Two groups of patients before the start of treatment in all 7 days after treatment and determination of lung function and arterial blood gas.Results The lung function and arterial blood gas relatively before treatment will be improved obviously （P〈0.05）.Conclusion Combined oxygen atomization sucked bromlnated isopropyl tetramin methenamlne and salbutomol of COPD patients with acute exacerbations period of pulmonary function and natural role has improved remarkably.