血清唾液酸检测在肾功能衰竭中的临床意义

目的研究急、慢性肾功能衰竭患者血清中唾液酸水平的变化及其临床意义。方法选取2006年10月至2010年5月本院收治的肾功能衰竭患者60例(观察组),采用单一试剂显色法测定唾液酸,并与同期本院健康体检者40名(对照组)比较。结果观察组患者血清唾液酸水平明显高于健康对照组,差异有统计学意义(P<0.05),观察组患者中,急性肾功能衰竭患者血清唾液酸水平,高于慢性肾功能衰竭患者,2组比较差异有统计学意义(P<0.05)。结论肾功能衰竭患者中血清唾液酸水平明显增高,唾液酸水平的测定对于肾功能衰竭患者病情判定临床治疗等具有指导意义。

Objective To study the acute and chronic renal failure serum sialic acid level and its clinical significance.Methods In October 2006 to May 2010 renal failure admitted to our hospital 60 patients （observation group）,a single determination of sialic acid color reagent,and with the same hospital were 40 healthy patients （control group） to compare.Results The levels of serum sialic acid levels were significantly higher than control group, the difference was statistically significantG~〈0.05）,patients in the observation group,patients with acute renal failure serum sialic acid level,higher than in patients with chronic renal failure, There were significant differences between the two groups（P〈0.05）.Conchusion Patients with renal failure significantly increased the level of serum sialic acid,sialic acid in serum renal failure for the clinical treatment of patients with the disease to deter-- mine significance.