幽门螺杆菌相关性消化性溃疡治疗的研究

目的观察幽门螺杆菌(HP)相关性消化性溃疡(胃/十二指肠溃疡)根除HP治疗的常用三联治疗方案7d疗程和14d疗程的疗效和安全性。方法将60例HP检测(尿素酶法)阳性的消化性溃疡患者随机分为A组和B组各30例,A组治疗7d,B组治疗14d,观察HP根除情况,溃疡愈合情况以及不良反应。结果临床总有效率B组明显优于A组(P<0.01)。结论 14d疗程明显优于7d疗程,药物不良反应无明显增加。

Objective To observe the efficacy and safety of the commonly used triple therapy program for 7 days＇ cure and 14 days＇ cure to eradicate helicobacter pylori associated peptic ulcer.Methods First divide 60 cases detected HP （urea enzymatic） positive peptic ulcer patients randomly into Group A and Group B（each with 30 cases）.Group A was given the treatment of 7 days and group B of 14 days.Then observe the eradication of Helicobacter Pylori,nlcer conglutination,and side effect.Results The total effective rate was significantly higher in group B than in group A（P〈0.01）.Conclusion The 14 days＇ cure were obviously better than the 7 days＇ cure,no significant increase of drug adverse reactions.