摘要
对合成的5种苯并异噻唑啉酮类化合物进行了生物活性研究。抑菌试验结果表明,化合物a与化合物b对大肠杆菌最小抑菌浓度为12.5mg/L。对金黄色葡萄球菌都表现出良好的抑菌活性。对亚心形扁藻,蛋白核小球藻,球等鞭金藻,化合物都有抑制其生长的活性,亚心形扁藻耐受性最高,球等鞭金藻的耐受性最低,蛋白核小球藻的耐受性居中。
The biological activity of five N-substituted phenyl-2-（benzo-isothiazolin-3-one-2-yl） carbonyl amines was studied.The result showed that compounds a and compounds b of 12.5mg/L had activity against Escherichia coli.The five compounds showed good antibacterial activity to Staphylococcus aureus.All compounds inhibited the growth activity to the microorganisms like heart-shaped flat on the sub-algae,Chlorella pyrenoidosa,Isochrysis galbana.Among those,the highest activity was the Platymonas subcordiformis,the lowest was Isochrysis galbana.
出处
《生物学杂志》
CAS
CSCD
2011年第4期7-9,共3页
Journal of Biology
基金
国家自然科学基金(20962007)
关键词
苯并异噻唑啉-3-酮
抑藻
抑菌
benzisothiazole-3-one
inhibition of algal
antibacterial
