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氯吡格雷联合拜阿司匹林治疗老年急性脑梗死疗效观察 被引量:21

Oberservation of clopidogrel and aspirin combination treatment on acute cerebral infarction in elderly patients
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摘要 目的探讨氯吡格雷联合拜阿司匹林治疗老年急性脑梗死的疗效和安全性。方法120例急性脑梗死随机分为三组。治疗组40例,氯吡格雷组40例,拜阿司匹林组40例。在常规治疗基础上。治疗组加用氯吡格雷和拜阿司匹林,氯吡格雷组加用氯吡格雷,拜阿司匹林组加用拜阿司匹林治疗。治疗14d后,观察三组用药前后疗效及安全性。结果治疗组能明显改善脑梗死局灶神经功能缺损症状(P〈0.05),疗效优于氯吡格雷组和拜阿司匹林组;三组对出凝血指标无明显影响(P〉0.05)。结论氯吡格雷联合拜阿司匹林治疗急性脑梗死安全有效,并能明显改善急性脑梗死患者的局灶神经功能缺损症状,效果优于单独应用氯吡格雷或拜阿司匹林。
出处 《神经疾病与精神卫生》 2011年第4期359-361,共3页 Journal of Neuroscience and Mental Health
关键词 拜阿司匹林 老年急性脑梗死 氯吡格雷 Aspirin Acute cerebral infarction Clopidogrel
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