老年冠心病患者合并肾功能不全临床特点分析

Analysis of Clinical Aspects for Elderly with combined Coronary Heart Disease and Renal Dysfunction

目的探讨老年冠心病患者合并肾功能不全的临床特点。方法回顾分析我院收治的120例老年冠心病患者的临床资料,根据入院时测定的血清肌酐值和MDRD公式估测肾小球滤过率(eGFR),将120例患者分为肾功能不全组(eGFR<60mL/min)和肾功能正常组。对比观察住院期间不良心血管事件的发生率。结果 120例患者中,肾功不全发生率44%。肾功能不全组与对照组比较,急性心肌梗死、心衰发生率及住院期间病死率均显著高于对照组(P<0.001);糖尿病发生率高于对照组(P<0.05)。结论合并肾功能不全的老年冠心病患者中,急性心肌梗死、心衰发生率高,多合并糖尿病,住院期间病死率高。

Objective To explore the clinical aspects of elderly with combined coronary heart disease（CHD） and renal dysfunction.Methods 120 elderly with coronary heart disease were divided into 2 groups（renal dysfunctional group and nor-- mal remd functional group） based on their value of blood serum creatinine and estimated glomerular filtration rate（eGFR） determined by the MDRD equation.The incidence of adverse cardiovascular events were analyzed.Results Fifty--three pa- tients（44%） were considered as renal dysfunctional group.The incidence of acute myocardial infarction,heart failure and rate of mortality was significantly higher in patients with renal dysfunctional group compared to the normal renal func- tional group（P〈0.001）;furthermore,patients in renal dysfunctional group revealed a higher incidence of Type 2 Diabetes occurrence as shown with a significant difference（P〈0.05）.Conclusion A greater incidence of acute myocardial infarction and heart failure was associated with elderly with CHD combined with renal dysfunction,as well as an increased the rate of Type 2 Diabetes occurrence and mortality in hospital.