针吸细胞学诊断色素性基底细胞癌的探讨

Significance of Fine-needle Aspiration Cytology in the Diagnosis of Pigmented Basal Cell Carcinoma

目的探讨针吸细胞学在色素性基底细胞癌临床诊断中的价值。方法收集经病理确诊的13例色素性基底细胞癌病例进行针吸细胞学检查,对其临床表现及针吸细胞学特点进行分析。结果针吸细胞学具有特征性镜下形态学特点:包括大量基底细胞样肿瘤细胞呈巢团状分布,可见外周细胞呈栅栏状排列,散在分布的细胞较少,细胞内外均易见明显黑色素颗粒。所有病例均经病理诊断证实为色素性基底细胞癌。结论针吸细胞学诊断该病不但快速、损伤小、操作简便并且准确率高,对临床治疗方式及手术范围的选择有指导意义。

Objective To study the clinicopathologic features and cytological features of pigmented basal cell carci- noma （pBCC） and differential diagnosis. Methods Thirteen cases of pBCC in our hospital are com- paratively analyzed of their histopathological and cytological features. Some related papers are reviewed. Results A large amount of cancer cells like basal cell can be found in compact distribution, and a few amount of them scattered around. Portion of cell conglomeration was arrayed like fence-barrier. Melanin granules can be identified clearly in most of the cells. All the cases were testified to be PBCC through pathological diagnosis. Conclusion Fine-Needle Aspiration Cytology （FNAC） is an accurate, timesav- ing and slight-injuring method for the diagnosis of pBCC and is helpful for clinical treatment and extent of surgery.