色素性痒疹1例

A Case of Prurigo Pigmentosa

患者女,24岁。前胸和上背部起瘙痒性丘疹2年半,皮损反复发作,逐渐融合成网状,消退后遗留色素沉着。皮损组织病理示:表皮轻度棘层肥厚,海绵形成,基底细胞灶状液化变性,真皮浅层血管周围单一核细胞浸润,散在噬黑素细胞。诊断:色素性痒疹。给予米诺环素100mg/d,1周后瘙痒消失,红色丘疹基本消退,遗留网状色素沉着斑。

A 24-year-old woman had intensely pruritie papules on her upper back and chest for two years and a h^f. Papules recurred shortly afterwards and gradually progressed into a reticular pattern and resolved leaving pig- mentation. Histopathology showed slightly epidermal acanthosis with focal spongiosis and vacuolar alteration at the dermo-epidermal junction. Superficial perivascular infiltrate of lymphocytes and sparsed melanophages was also observed. Diagnosis： Prurigo pigmentosa. The patient was given oral minocycline 100mg daily and within 1 week the pruritus and inflammatory papules of skin disappeared and leaved reticular pigmentation.