520例儿童支气管哮喘过敏原点刺试验临床分析

Clinical Analysis on 520 Children with Bronchial Asthma of Allergens by Skin Prick Test

目的:通过点刺液过敏原筛查引起本地区支气管哮喘的过敏原状况,从而达到有效的防控。方法:采用阿罗格标准化生产的点刺液筛查支气管哮喘过敏原,对520例哮喘儿童和300例健康儿童进行诊断。结果:520例患者中324例(62.7%)呈阳性。324例皮肤点刺试验中屋尘螨阳性率最高,其次是粉尘螨等。屋尘螨和粉尘螨支气管哮喘患儿与对照组变应原皮肤点刺试验阳性结果(p<0.001),为差异有显著统计学意义。结论:屋尘螨和粉尘螨是三峡库区地区支气管哮喘重要过敏原。

Objective：To analyze the allergy status of asthma by skin-prick test in Three Gorges Reservoir Area.Methods：520 children with asthma and 300 healthy controls were enrolled and the standardized prick solution from Allergopharma was used in this study.Results：324（62.7﹪）skin prick test positive cases were found in 520 cases with asthma.Dermatophagoides pteronyssinus were the main allergens and followed by dermatophagoides culinae in the study.Compared with the control group,the positive rate of dermatophagoides pteronyssinus and dermatophagoides culinae in asthma group was significant higher（p0.001）.Conclusion：Dermatophagoides pteronyssinus and dermatophagoides culinae were important allergens for children with asthma in Three Gorges Reservoir Area.