窄带成像内镜诊断慢性萎缩性胃炎的临床价值

Clinical value of narrow-band imaging for diagnosis of chronic atrophic gastritis

目的探讨窄带成像(narrow-bandimaging,NBI)内镜诊断慢性萎缩性胃炎的临床价值。方法选取78例临床疑诊慢性萎缩性胃炎的患者依次进行普通内镜、NBI及病理学检查,并进行比较。结果在NBI模式下,对慢性萎缩性胃炎诊断的敏感性、特异性、阳性预测值、阴性预测值分别为73.842%、84.61%、96.00%、39.29%。远高于普通内镜组的49.23%、61.53%、86.49%、19.51%;在NBI组48例阳性病例中,伴肠化生17例,伴轻度异型增生19例,伴重度异型增生3例,亦显著高于普通内镜组的6、8、1例(P<0.05)。结论 NBI可明显提高诊断慢性萎缩性胃炎的准确率,且操作简便、快捷。

Objective To evaluate the role of narrow-band imaging endoscopy for diagnosis of chronic atrophic gastritis. Methods Seventy-eight patients with suspected chronic atrophic gastritis were underwent conventional endoscopy, narrow-band imaging endoscopy, and histopathological examination, then the data were compared. Results The sensitivity, specificity, positive predictive value, negative predictive value for chronic atrophic gastritis by narrow-band imaging mode were 73.842%, 84.61%, 96.00%, 39.29%, respectively, which were significantly higher than that obtained by conventional endoscopy（49.23%, 61.53%, 86.49%, 19.51%, respectively）. In narrow-band imaging endoscopy group, 48 patients were positive which included 27 patients with intestinal metaplasia, 19 cases with mild hyperplasia, and 3 patients with severe hyperplasia, while in conventional endoscopy group, only 6 patients with intestinal metaplasia, 8 patients with mild hyperplasia, and 1 patient with severe hyperplasia were detected （P 0.05）. Conclusion Endoscopic narrow-band imaging can improve the diagnostic accuracy of chronic atrophic gastritis.