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来曲唑与克罗氯米芬促排卵治疗多囊卵巢综合征临床分析 被引量：12

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摘要 目的探讨来曲唑用于多囊卵巢综合征(PCOS)患者的促排卵临床效果。方法符合PCOS诊断的不孕患者262例分为两组,来曲唑(LE)组132例,5mg/d,克罗米芬(CC)组130例,100mg/d。用药时机:月经来潮或撤退性出血第4天起服用药物,连服5d;每组均同期纪录卵泡发育、排卵率、妊娠率、多胎妊娠率等指标。结果 LE促排卵治疗132例患者198个周期中183个周期有排卵,11个周期发生黄素化卵泡未破裂综合征(LUFS),未出现卵巢过度刺激综合征(OHSS),妊娠率19.2%。CC促排卵治疗130例患者193个周期中168个周期有排卵,22个周期发生LUFS,妊娠率15.0%。结论 LE用于PCOS患者,具有良好的排卵率,而妊娠率无显著差异,LE是否能替代CC作为一线的促排卵药还有待于临床进一步的研究。
作者 黄朝霞 房梅芳
机构地区 南京市江宁区妇幼保健所
出处 《江苏医药》 CAS CSCD 北大核心 2011年第16期1945-1946,共2页 Jiangsu Medical Journal
关键词 来曲唑 克罗米芬 促排卵 不孕症
分类号 R711 [医药卫生—妇产科学]
  • 相关文献

参考文献6

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二级参考文献42

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共引文献191

同被引文献79

  • 1任长安.耐克罗米芬的多囊卵巢综合征治疗研究进展[J].中国性科学,2007,16(11):32-36. 被引量：2
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  • 3Abd Elgafor I.Efficacy of combined metformin-letrozole in comparison with bilateral ovarian drilling in clomiphene-resistant infertile women with polycystic ovarian syndrome.Arch Gynecol Obstet,2013,288(1):119-123.
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二级引证文献74

江苏医药
2011年 第16期

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