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心肌肌钙蛋白I、肌红蛋白和肌酸激酶同工酶在老年急性心肌梗死中的检测及意义 被引量:9

The detection and significance of cardiac troponin I, myoglobin and creatine kinase MB in old patients with acute myocardial infarction
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摘要 目的探讨心肌肌钙蛋白I(cTnI)、肌红蛋白(Mb)和肌酸激酶同工酶(CK.MB)在老年急性心肌梗死(AMI)中的变化及意义。方法分别检测89例AMI患者(AMI组)和100例体检的健康人(对照组)cTnI、Mb、CK-MB水平,并进行比较。结果AMI组cTnI、Mb、CK-MB水平分别为(8.15±3.26)μg/L、(478.45±96.87)μg/L和(128.17±53.26)U/L,而对照组分别为(0.03±0.02)μg/L、(21.61±9.38)μg/L和(9.53±2.94)U/L,AMI组cTnI、Mb、CK-MB水平显著高于对照组(P〈0.05)。cTnI、Mb、CK.MB检测AMI的敏感度分别为95.5%(85/89)、97.8%(87/89)和87.6%(78/89),特异度分别为98.0%(98/100)、82.O%(82/100)和94.0%(94/100)。结论cTnI、Mb和CK-MB水平在老年AMI患者中明显升高,其中cTnI在诊断AMI时具有很高的敏感度和特异度。 Objective To explore the changes and significances of cardiac troponin I (cTnI), myoglobin (Mb) and creatine kinase MB (CK-MB) in old patients with acute myocardial infarction(AMI). Method The levels of cTnI, Mb and CK-MB in 89 cases with AMI patients (AMI group) and 100 healthy controls (control group) were detected and compared. Results The levels ofcTnI, Mb and CK-MB in AMI group were (8.15 ± 3.26) μg/L, (478.45 ± 96.87 ) μg/L and ( 128.17 ± 53.26) U/L, while were (0.03 ± 0.02) μg/L, (21.61 ±9.38) μg/L and (9.53± 2.94) U/L in control group, the levels of cTnI, Mb and CK- MB in AMI group were significantly higher than those in control group(P 〈 0.05 ). The sensitivity rate of cTnI, Mb and CK-MB for detecting AMI was 95.5% (85/89), 97.8% (87/89) and 87.6% (78/89), and the specificity rate was 98.0% (98/100), 82.0% (82/100) and 94.0% (94/100). Conclusion The levels of cTnI, Mb and CK-MB are significantly increased in AMI patients, which cTnI for detecting AMI has high sensitivity and specificity.
出处 《中国医师进修杂志》 2011年第24期7-9,共3页 Chinese Journal of Postgraduates of Medicine
关键词 肌钙蛋白I 肌红蛋白 肌酸激酶 MB型 心肌梗死 Troponin I Myoglobin Creatine kinase, MB form Myocardial infarction
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