针灸配合药物治疗抑郁症临床观察

Clinical Observations on Acupuncture and Moxibustion plus SSRIs for the Treatment of Depression

目的观察针灸配合药物治疗抑郁症的临床疗效。方法 80例抑郁症患者随机分为药物组30例,采用单纯SSRI类药物治疗;针药组25例,采用针刺配合SSRI类药物治疗;灸药组25例,采用针刺加艾灸配合SSRI类药物治疗。分别观察三组治疗前和治疗后1、2、4、6星期HAMD量表总评分情况,采用HAMD量表评定疗效。结果灸药组、针药组总有效率均为100.0%,与药物组总有效率(83.3%)比较差异均有统计学意义(P<0.01)。灸药组和针药组在治疗1、2、4、6星期HAMD总分改善明显优于药物组(P<0.01)。灸药组在第2星期起HAMD减分率大于针药组和药物组,减分率比较差异均有统计学意义(P<0.05)。结论针刺加艾灸配合SSRI类药物治疗抑郁症疗效优于单用SSRI类抗抑郁药,且起效速度快。针刺配合SSRI类药物的治疗也有类似的疗效,但针刺加艾灸配合药物治疗对改善患者抑郁情绪、减少HAMD量表积分具有一定的优越性。

Objective To investigate the clinical efficacy of acupuncture and moxibustion plus SSRIs in treating depression.Methods Eighty depression patients were randomly allocated to a medication group of 30 cases treated with SSRIs alone,an acupuncture plus medicine group of 25 cases treated with acupuncture plus SSRIs and a moxibustion plus medicine group of 25 cases treated with acupuncture and moxibustion plus SSRIs.The HAMD scale score was counted in the three groups before treatment and at 1,2,4 and 6 weeks after.The therapeutic effects were evaluated using the HAMD scale.Results The total efficacy rate was 100.0% in both the moxibustion plus medicine and acupuncture plus medicine groups.There was a statistically significant difference compared with the total efficacy rate（83.3%） in the medication group（P0.01）.The HAMD score was significantly lower at 1,2,4 and 6 weeks after treatment in the moxibustion plus medicine and acupuncture plus medicine groups than in the medication group（P0.01）.The HAMD score reduction rate was larger from the second week in the moxibustion plus medicine group than in the acupuncture plus medicine and medication groups.There was a statistically significant difference in the score reduction rate（P0.05）.Conclusions Acupuncture and moxibustion plus SSRIs are more effective than SSRIs alone in treating depression and produce a quick effect.Acupuncture plus SSRIs has a similar therapeutic effect,but acupuncture and moxibustion plus medicine have a certain advantage in relieving the patient＇s depression and decreasing the HAMD scale score.