膜式病变细胞采集术用于支气管肺泡灌洗液细胞学检查在周围型肺癌诊断中的价值

The Value of Membrane Pathological Cellular Collection in Cytologic Examination of Bronchoalveolar Lavage Fluid in Diagnozing Peripheral Lung Cancer

目的评价膜式病变细胞采集制片技术用于支气管肺泡灌洗液(BALF)细胞学检查对周围型肺癌的诊断价值。方法收集115例周围型肺癌患者经纤支镜取支气管肺泡灌洗液分别用膜式病变细胞采集术及常规离心涂片细胞学检查与钳取活检、刷片病理学检查对比。结果用膜式病变细胞采集术收集处理BALF癌细胞阳性率占(71.30%),与常规离心涂片癌细胞阳性率占(69.47%)相比,P>0.01,与钳取活检(40.87%)、刷片(35.65%)相比,P<0.01。结论 BALF细胞学检查对周围型肺癌具有较好的诊断价值,膜式病变细胞采集制片技术用于支气管肺泡灌洗液细胞学检查有助于阅片及病理诊断。

Objective To evaluate the value of membrane pathological cellular collection in cytologic examination of bronchoalveolar lavage fluid（BALF） in diagnosing peripheral lung cancer.Methods BALF of 115 cases with peripheral lung cancer were collected through bronchofiberscope,membrane pathological cellular collection and conventional centrifugal smear were made,and the results were compared with those of protractor biopsy and brushing pathological study.Results The positive rate of cancer cells processed by membrane pathological cellular collection was 71.3% while that of cancer cells processed by conventional centrifugal smear was 69.47%（P0.01）;the positive rate of cancer cells processed by protractor biopsy was 40.87% and that by brushing was 35.65%（P0.01）.Conclusions BALF cytologic examination is of good diagnostic value for peripheral lung cancer,the application of membrane pathological cellular collection in cytologic examination of BALF is helpful for slice reading and pathological diagnosis.