倍生颗粒治疗血液透析患者微炎症状态临床观察

Effect of Beisheng Granula on Microinflammation Status in Hemodialysis Patients with Chronic Renal Failure

目的:倍生颗粒对血透患者微炎症状态影响。方法:选取慢性肾衰竭血液透析患者80例,随机分为治疗组及对照组,每组40例,观察治疗前后患者一般症状、体征的变化,测定治疗前后即透前观察患者治疗前及治疗结束后均检测前白蛋白(Pre-Alb)、白蛋白(Alb)、转铁蛋白(SF)的浓度、血白细胞介素6(IL-6)、超敏C反应蛋白(hs-CRP)、体重指数(BMl)。结果:治疗组血清白蛋白、前白蛋白及转铁蛋白、血白细胞介素6、超敏C反应蛋白、体重指数与治疗后及对照组相比均有显著改善P<0.05,治疗组SGA评分与治疗前及对照组相比有明显改善(P<0.01)。结论:倍生颗粒可改善血透患者的微炎症状态。

Objective：To observe the effects of beisheng granula on microinflammation status in hemodialysis patients with chronic renal failure.Methods：The 80 patients were divided into beisheng granula group（n=40）and control group（n=40）randomly.The score of Subjective global assessment（SAG）of nutrition and BMI were measured before and after treatment.The serum level of albumin,pre-albumin,transferring,IL-6 and hs-CRP were also determined.Results：In beisheng granula group,the level of albumin,pre-albumin and transferring and the score of SGA and BMI were increased,while the level of IL-6 and hs-CRP were decreased significantly compared with before treated and the control group.Conclusion：Beisheng granules can improve microinflammation status in hemodialysis patients with chronic renal failure.