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机体免疫功能与带状疱疹相关性研究 被引量:4

Correlation Between Immune Function and Herpes Zoster
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摘要 目的:探讨机体免疫功能与带状疱疹的相关性。方法:选取2007年3月-2009年3月我院接诊的带状疱疹患者53例,设为患病组,另选取同期健康患者53例设为对照组,对两组患者采用流式细胞术对CD4T淋巴细胞的改变进行检测,同时对患病组不同年龄段患者的CD4T淋巴细胞的改变进行检测,以探讨CD4T淋巴细胞的改变与带状疱疹的相关性。结果:与对照组比较,患病组CD3、CD4、CD4/CD8显著降低,CD8显著升高,两组比较差异有统计学意义(P<0.05);与非老年患病组比较,老年患病组患者CD3、CD4、CD4/CD8显著降低,CD8显著升高,两组比较差异有统计学意义(P<0.05)。结论:带状疱疹的发生与CD4T淋巴细胞的降低密切相关,同时老年人为带状疱疹的易感人群。 Objective:To research the correlation of immune function and herpes zoster.Methods:From March 2007 to March 2009 of hospital admissions 53 patients with Herpes Zoster of were in the sick group while the other 53 patients selected for the same period in healthy control group.CD4 T lymphocytes by flow cytometry changes of two groups were detected,while the sick group of patients of different ages to detect changes in CD4T lymphocytes to explore the changes CD4T lymphocytes associated with herpes zoster.Results:Compared with control group,the sick group of CD3,CD4,CD4/CD8 were significantly decreased,CD8 was significantly higher,the difference was statistically significant(P0.05).Compared with the non-elderly sick,elderly sick group of patients with CD3,CD4,CD4/CD8 were significantly decreased,CD8 was significantly higher,the difference was statistically significant(P0.05).Conclusion:The occurrence of herpes zoster is closely related to the decrease CD4T lymphocytes,while the elderly are susceptible to herpes zoster.
作者 李晓斌
出处 《医学理论与实践》 2011年第15期1779-1780,共2页 The Journal of Medical Theory and Practice
关键词 机体免疫功能 带状疱疹 相关性研究 Immune function Herpes zoster Correlation
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