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卒中遗传学研究进展 被引量:1

Advances in stroke genetics
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摘要 无论是在中国和全世界范围内,卒中都是一种重要的公共卫生问题。近年来,卒中遗传学研究取得了很大进展,特别是全基因组关联研究(genome-wide association study,GWAS)和表观遗传学的出现给该领域带来突破性进展。它们分别从基因水平和环境因素层面研究卒中的发病机制。虽然目前仍存在众多问题,但卒中遗传学前景光明。 Stroke is an important public health problem both in China and worldwide. Stroke gentetics research has made great progess in recent years, especially the genome-wide association study (GWAS) and the emergence of epigenetics, has brought a breakthrough in this field. They studied the pathogenesis of stroke from the ~naetic level and the environmental factor levels. Although there are still many problems to be solved, the prospect of stroke genetics is bright.
出处 《国际脑血管病杂志》 北大核心 2011年第7期481-487,共7页 International Journal of Cerebrovascular Diseases
关键词 卒中 全基因组关联研究 后成说 遗传 表观基因组 多态现象 单核苷酸 DNA甲基化 组蛋白类 Stroke Genome-wide association study Epigenesis, genetic Epigenomics Polymorphism, single nucleotide DNA methylation Histones
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同被引文献17

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