妊娠期肝内胆汁淤积症的临床分析

Clinical analysis of intrahepatic cholestasis of pregnancy

目的探讨妊娠期肝内胆汁淤积症(ICP)妊娠的结局。方法选取ICP产妇32例为研究组,同期非ICP产妇70例为对照组,将两组妊娠结局进行比较。结果研究组早产、新生儿窒息的发生率均高于对照组(P<0.01),胎膜早破、产后出血发生率及剖宫产率也均高于对照组(P<0.01)。结论妊娠期肝内胆汁淤积症妊娠的结局主要是早产、剖宫产率与新生儿窒息率和围生儿死亡率升高。

Objective To research the pregnancy outcomes of intrahepatic cholestasis of pregnancy （ICP）. Methods The pregnancy outcomes of 32 ICP（ study group）and 70 cases whithout ICP（ control group）were analysed. Results Premature,neonatal asphyxia and mortality rate in study group were increased significantly compared with control group （all P 〈 0.01 ）. There was significant difference in incidence of premature rupture of membrane, the postpartum hemorrhage,caesarean operation between the two groups （ all P 〈 0. 01 ）. Conclusion The main pregnancy outcomes were the increase of the premature delivery rates, caesarean operation, neonatal asphyxia rates and the mortality rates.