景宁县居民2型糖尿病危险因素病例对照研究

Risk factors of type 2 diabetes among residents of Jingning county:a case-control study

目的了解浙江省景宁县居民2型糖尿病相关危险因素,为采取相应的干预措施提供参考依据。方法采用以医院为基础病例对照研究方法对2009年1-12月在浙江省景宁县人民医院就诊的501例2型糖尿病患者及同期健康体检的501名非糖尿病健康人群进行2型糖尿病相关危险因素的问卷调查。结果病例组一级亲属糖尿病史、喜食糖与甜食、常吃油炸食品、经常饮酒、常喝饮料、高血压史、高血糖史、平时精神易紧张和激动、生育巨大胎儿比例分别为19.36%,72.46%,60.08%,40.52%,28.74%,34.33%,10.98%,16.97%,16.97%;对照组分别5.39%,36.73%,25.55%,29.94%,21.16%,5.99%,1.00%,4.59%,4.79%,差异均有统计学意义(P<0.01);多因素条件Logistic回归分析结果表明,一级亲属糖尿病史、喜食糖与甜食、常吃油炸食品、经常饮酒、常喝饮料、高血压史、高血糖史、平时精神易紧张和激动、生育巨大胎儿是景宁县居民患2型糖尿病的主要危险因素。结论遗传、有不良饮食习惯、有慢性病史、精神紧张和生育巨大胎儿的居民更易患2型糖尿病。

Objective To study the risk factors of type 2 diabetes among residents of Jingning county,Zhejiang province and to provide reference for intervention measures. Methods A hospital-based case-control study was conducted from January to December ,2009 among 501 patients with type 2 diabetes patients and 501 healthy subjects with a questionnaire survey. Results Among the cases, the proportions of diabetes history among first-degree relatives, preference for sweets, eating fried foods, frequent alcohol consumption, drinking beverages frequently, history of hypertension, history of high blood sugar,tending to be stress or excitement, and history of giving a birth to macrosonia were 19. 36% ,72. 46% ,60.08%, 40. 52% ,28.74% ,34. 33% , 10. 98%, 16. 97%, and 16. 97% ,respectively, and significantly higher than those of the control group （ 5.39% ,36. 73% ,25.55% ,29. 94% ,21.16% ,5.99% ,1.00% ,4. 59% ,and 4.79% ） （P 〈0.01 for all）. Multivariate logistic regression analyses showed that family history of diabetes, preference for sweets, eating fried foods, alcohol and beverage consumption, history of hypertension, history of high blood sugar, tending to stress or excitement, and giving a birth to macrosonia were major risk factors for type 2 diabetes among the residents of Jingning county. Conclusion Residents with some genetic factor, unheathy eating habits, chronic disease, mental stress, and giving birth to macrosonia are more prone to have type 2 diabetes.