子宫普通平滑肌瘤和富细胞平滑肌瘤超微结构比较

The Compare of Ultrastructural in Common and Cellular of Uterine Leiomyoma

目的:探讨电镜诊断子宫富细胞平滑肌瘤的价值。方法:选择由光镜诊断的普通平滑肌瘤组织标本10例和富细胞平滑肌瘤组织标本11例,分别在电镜下进行组织超微结构的观察。结果:两类平滑肌瘤细胞均表现为胞质丰富;在胞质中充满肌丝、密体、密斑。但富细胞平滑肌瘤的细胞排列紊乱、形态不规则;胞浆内线粒体、高尔基复合体、溶酶体和粗面内质网明显增多;细胞核增大、有异型性;可见核内假包涵体。结论:富细胞平滑肌瘤的超微结构与普通平滑肌瘤有一定差异,表现为代谢功能活跃,一定程度上缺乏分化。

Objective：To inquire into the diagnostic value of electronic microscope in cellular uterine leiomyoma. Methods：To select tissue specimen of common leiomyoma（n=10）and cellular leiomyoma（n=11）,which diagnosed by optical microscope,and to observe by electronic microscope separately. Results：The myofilaments,dense bodies and dense spots were very abundant in cytoplasm both of them,but in cellular leiomyoma,the arrange of cell was disorder and the shape of cell was unregular. The mitochondria,rough endoplasmic reticulum, cytolysosomes,golgiosomes in cytoplasm were increase obviously. The nucleolus was big and atypia. There were false inclusions in nucleolus. Conclusions：The ultrastructures were different between cellular and common leiomyoma. The metabolism of cellular leiomyoma was brisk and lack differentiation to a certain degree.