南川卫矛的化学成分研究

Chemical Constituents of Euonymus bockii Loes.

采用硅胶和Sephalex LH-20凝胶色谱柱层析等分离方法对南川卫矛茎提取物的乙酸乙酯组分的化学成分进行了分离纯化,并根据理化性质和核磁共振、质谱等波谱数据进行了结构鉴定。分离得到了11个三萜类化合物,分别鉴定为:木栓酮、3-O-木栓烷-28-羧酸、29-羟基-3-木栓酮、大子五层龙酸、直楔草酸、雷公藤内酯甲、雷公藤内酯乙、3-羟基-2-O-3-无羁萜烯-29-羧酸、3-羟基-2、24-O-3-无羁萜烯-29-羧酸、20(29)-羽扇豆烯-1β,3β-二醇、20(30)-羽扇豆烯-3β,29-二醇。

Chemical constituents of Euonymus bockii Loes.stem were isolated and purified by silica gel and sephadex LH-20 column chromatography.Their structures were elucidated by chemical and spectroscopic methods.Eleven compounds were identified as friedelin,3-O-28-friedelanoic acid,29-hydroxy-3-friedelanone,salaspermic acid,orthosphenic acid,wilforlide A,wilforlide B,3-hydroxy-2-O-3-friedelen-29-oic acid,3-hydroxy-2,24-dioxo-3-friedelen-29-oic acid,20（29）-lupene-1β,3β-diol,and 20（30）-lupene-3β,29-diol.