保和丸加减治疗肥胖型糖耐量减低60例临床观察

Observation on the effect of Baohe pills on 60 obese patients with impaired glucose tolerance

目的观察中药保和丸加减对糖耐量减低(IGT)人群糖尿病发生率的影响。方法选择无临床症状肥胖型糖耐量减低人群90例,按体检序号随机分为治疗组60例和对照组30例。对照组给予控制饮食及运动锻炼,治疗组在对照组干预的基础上,加服保和丸加减汤,2组疗程均为6个月。观察2组干预后糖尿病的发生率和IGT的逆转率。结果治疗组糖尿病的发生率为3.3%I,GT的逆转率为21.7%,对照组糖尿病的发生率为13.3%I,GT的逆转率为6.7%,两组比较差异有统计学意义(P<0.05)。结论中药保和丸加减对肥胖型IGT患者干预治疗可减少糖尿病的发生率。

Objective To observe the effect of Baohe pills on patients with impaired glucose tolerance（IGT）.Methods Ninty IGT without clinical symptoms were divided into observation group（60 cases） and control group（30 cases） based on randomly serial number.The patients in the control group were treated with controlled diet plus physical practice and those in the observation group were given Baohe pills plus controlled diet and physical practice for a course of 6 months.Results The incidence rate of diabetes in observation group was 3.3% and A IGT conversion rate of 21.7%.The incidence rate of diabetes in the control group was 13.3% and a IGT conversion rate of 6.7%,showing significant differences between the two groups（P0.05）.Conclusion Baohe pill can reduce the incidence rate of diabetes in obese IGT cases.