摘要
一系列 Mannich 底被三部件的 Mannich 反应综合。最新综合的混合物被元素的分析,红外, NMR 和集体分光镜的研究很好描绘。综合混合物的潜在的抗菌剂效果用标准细菌的种类被调查:克积极、克否定的细菌。有趣地,所有综合混合物被观察正在答应领先,拥有对重要禁止的活动中等同样与相比标准。
A series of Mannich bases were synthesized by a three-component Mannich reaction. The newly synthesized compounds were well characterized by elemental analyses, IR, NMR and mass spectroscopic studies. The potential antibacterial effects of the synthesized compounds were investigated using standard bacterial strains: Gram-positive and Gram-negative bacteria. Interestingly, all the synthesized compounds were observed to be promising leads, possessing moderate to significant inhibitory activity as compared to standard.