结肠透析结合利尿合剂灌肠治疗肝硬化腹水的疗效观察

Effect of Colon Dialysis and Diuretics Enteroclysis on Cirrhosis Ascites

目的探讨对结肠透析结合利尿合剂灌肠治疗肝硬化腹水的疗效。方法将怀化市第二人民医院收治的82例肝硬化腹水患者,随机分为干预组(n=44例)和对照组(n=38例),对照组接受基础对症支持治疗,干预组在此基础上,接受结肠透析结合利尿合剂灌肠治疗。结果干预组与对照组的总有效率分别为84.1%、47.4%;干预组腹水消退时间明显缩短,血清内毒素水平显著下降,二者均差异具有统计学意义(P<0.05)。结论结肠透析结合利尿合剂灌肠治疗可有效消退腹水,且无电解质紊乱的风险。

Objective To explore the effect of colon dialysis and clysis therapy with diuretics enteroclysis on the treatment of cirrhosis ascites.Methods 82 patients with cirrhosis ascites in Huaihua Second People＇s Hospital were divided into intervention group（n=44） and control group（n=38）.All the cases were given routinely symptomatic and supportive treatment.Based on above the intervention group was treated with colon dialysis and clysis therapy with diuretics enteroclysis.Result The total effective rate of ascites was 84.1% in intervention group and 47.4% in control group,showing significant difference between group（P〈0.05）.The time for ascites extinction was shortened and the level of serum endotoxin was significantly reduced compared with control group（P〈0.05）.Conclusions Colon dialysis and clysis therapy with diuretics enteroclysis can contribute to ascites extinction and may not cause electrolyte imbalance.