肺部局限性磨玻璃样阴影与病理类型的相关性研究

Study on the Correlation between Focal Lung Ground Glass Opacity and Pathologic Changes

目的分析51例肺部局限性磨玻璃样阴影(fGGO)的随访结果,研究fGGO与病理类型的相关性。方法采用多排螺旋CT(MSCT)对fGGO进行定期观察,达到预设标准结束随访,手术明确病理类型;根据CT影像资料,判定fGGO的直径、类型、量化分型、形态。结果 51例患者中,有随访结果的45例。良性病变15例,恶性病变30例。fGGO的大小、类型在炎症性病变、BAC、腺癌、AAH四种病理类型间差异有统计学意义(P<0.01);fGGO病灶周边侵犯在低量化组与高量化组间差异有统计学意义(P<0.01)。结论 fGGO是肺癌的早期影像学改变,分析fGGO大小、类型、量化及其动态变化有助判断其病理类型及预后,为临床医生提供诊治方案。

Objective To analysis follow-up results of lung focal ground glass opacity （ fGGO ） in 51 patients, to investigate the correlation between fGGO and pathologic changes. Methods All patients were followed up with multirow spiral computed tomograph （ MSCT ） until meet preset standard. Categorized the diameter, category, quantization results and morphous. Results Forty five cases finished follow up. And 15 cases were benign, 30 cases were malignancy. There were significant differences among inflammatory lesion, bronchoalveolar cells cancer （ BAC ）, adenocarcinoma and atypical adenomatoid hyperplasia （ AAH ） in size or category of fGGO （ P 〈 0.01 ）. There were significant differences between lower quantization and higher quantization of fGGO in tumor peripheral infringement （ P 〈 0.01 ）. Conclusion Focal ground glass opacity is the early changes in lung cancer imaging. It is helpful in judgment pathology type and prognosis of lung cancer to analysis the size, category, quantization results and dynamic change of fGGO.