摘要
目的：探讨马鞭草的抗炎镇痛作用。方法：抗炎实验采用二甲苯致小鼠耳廓肿胀等常规抗炎模型；镇痛实验采用热板法和醋酸扭体法。结果：马鞭草提取物可明显抑制二甲苯致小鼠耳廊肿胀及角又菜胶引起的大鼠足跖肿胀，能显著抑制大鼠棉球肉芽肿的增重及醋酸致小鼠扭体反应，可明显延长热板引起小鼠疼痛反应的痛阈值。结论：马鞭草有明显的抗炎镇痛作用。
Objective： To study the anti-inflammatory and analgesic effects of Verbenaofficinalis. Methods： A few conventional models, such as the mouse pinna swelling induced by xylene; Analyesia experiments adopted hot-plate procedure and torsion body method. Results： Verbenaofficinalis obviously inhibited the swelling of mouse pinna induced by xylene, suppressed the edema of rat hind paw elicited by 1% carrageenan, significantly depressed the increase of proliferation of granuloma led by implanting wtton pellet and the torsion boby of rats. It had an abatement effect of algesin induced by heat with tail flick method. Condusion： Verbenaofficinalis is an effective medicine on anti-inflammatory.
关键词
马鞭草
抗炎
镇痛
Verbenaofficinalis
Anti-inflammation
Analyesia.
