摘要
目的:制备复方归芍妇康胶囊,建立其质量控制方法。方法:采用薄层色谱法对当归和益母草进行定性鉴别,采用HPLC对复方归芍妇康胶囊中的芍药苷进行含量测定。结果:芍药苷在0.303~1.515μg与峰面积呈良好的线性关系(r=0.9998);平均回收率为99.66%,RSD=0.27%(n=6)。结论:该制剂制备工艺稳定,含量测定方法准确可靠,重现性好,可用于复方归芍妇康胶囊的质量控制。
Objective :To prepare compound Guishao Fukang Capsules and establish its quality control method. Methods : TLC was used to identify Angelica sinensis and Herba leonuri, HPLC was used to determine the content of paeoniflorin in compound Guishao Fukang Capsules. Results:The linear ranges of paeoniflorin was 0. 303 - 1. 515μg ( r = 0. 999 8 ), the average recovery was 99.66 %, RSD was 0. 27 % ( n = 6). Conclusion: The preparation was stability, the content determination method was accurate reliable and reproducible and can be used in the quality control of compound Guishao Fukang Capsules.
出处
《中国现代中药》
CAS
2011年第8期31-33,共3页
Modern Chinese Medicine
关键词
复方归芍妇康胶囊
制备
芍药苷
HPLC
Compound Guishao Fukang Capsules
Preparation
Paeoniflorin
HPLC