沙美特罗与氟替卡松联合治疗支气管哮喘疗效分析

Effect analysis of saimeterol combind with fluticasone in treatment of bronchial asthma

目的:探讨沙美特罗与氟替卡松联合治疗支气管哮喘的临床疗效。方法:88例支气管哮喘患者随机分为对照组与观察组,每组44例,对照组给予平喘、镇咳、化痰、必要时吸氧等对症治疗,观察组在以上对症治疗的基础上联合应用沙美特罗及氟替卡松治疗,两组在治疗前及治疗3个月后测定第1秒用力呼气量(FEV1)、用力肺活量(FVC)及峰流速值(PEF),并对哮喘临床症状给予评分。结果:两组治疗后FEV1、FVC及PEF均较治疗前升高,治疗前、后差异有统计学意义(P<0.05),并且观察组疗效优于对照组(P<0.05);治疗后两组临床症状评分均降低,与治疗前相比差异有统计学意义(P<0.05),并且观察组症状改善情况明显优于对照组(P<0.05)。结论:沙美特罗与氟替卡松联合吸入治疗支气管哮喘可以有效控制哮喘症状,具有较好疗效,可临床推广应用。

Objective： Discuss the clinical effects of saimeterol combind with fluticasone in treatment of bronchial asthma.Methods： 88 cases were diagnosed as bronchial asthma patients were randomly divided into the treatment group and control group and 44 cases each group.Control group give relieving asthma,antitussive,phlegm,and,when necessary,such as oxygen symptomatic treatment,the treatment group in addition to the above the basis of symptomatic treatment the combined use of saimeterol and fluticasone in,Both groups in treatment before and after the treatment of three months was determined the forced expiratory volume in one second（FEV1） and forced vital capacity（FVC） and peak velocity value（PEF）,and clinical symptoms of asthma to score.Results： The values of the FEV1,FVC and PEF in the two group were all increased than before treatment,before and after the treatment with significant difference between,a statistically significant（P0.05）.After treatment,the two groups of the symptom score were all reduced,compared with before treatment with significant difference（P0.05）,and the treatment group symptoms improved significantly better than control group,a statistically significant（P0.05）.Conclusions：Saimeterol and fluticasone joint inhaled in treating bronchial asthma with can effectively control asthma,sympto-ms has good curative effect.