响应面优化提取决明子游离蒽醌工艺

Optimization of Extraction Process for Free Anthraquinone from Semen Cassiae by Response Surface Methodology

通过超声波提取对决明子中游离蒽醌的工艺条件进行探讨,研究乙醇体积分数、超声波温度、超声波时间和料液比对游离蒽醌提取率的影响。通过响应面试验方法对决明子中游离蒽醌的超声波提取工艺条件进行优化。结果表明,游离蒽醌提取的最佳工艺条件:以80%乙醇溶液为超声提取溶剂、液料比15:1(mL/g)、提取温度65℃、提取时间30min、超声功率100W,该条件下游离蒽醌的提取率为28.32%。因此采用响应面法优化得到的提取条件准确可靠,并且提取率较高,具有使用价值。

Anthraquinone is one of the major functional components in Cassia obtusifolia L.seeds.Response surface methodology was employed to optimize the ultrasonic-assisted extraction of free anthraquinone from Semen Cassiae.The extraction efficiency of free anthraquinone was investigated with respect to four process conditions including ethanol concentration,extraction temperature,ultrasonic treatment time and material-to-liquid ratio.The optimal conditions for anthraquinone extraction were 80% aqueous ethanol as the extraction solvent,material-to-liquid ratio of 15：1（mL/g）,extraction temperature of 65 ℃,ultrasonic treatment time of 30 min and ultrasonic power of 100 W.Under the optimal extraction conditions,the extraction rate of free anthraquinone from Semen Cassiae.was 28.32%.