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急性心理性应激诱发的神经内分泌反应及其影响因素 被引量:15

Neuroendocrine Response and Its Mediators Induced by Acute Psychosocial Stress
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摘要 急性心理性应激源分别通过下丘脑-脑垂体-肾上腺轴(hypothalamus-pituitary-adrenal axis,HPAA)和交感神经-肾上腺髓质轴(sympathetic-adrenal medulla axis)诱发神经内分泌反应。唾液皮质醇被认为是检测急性心理性应激所诱发的HPA轴反应的稳定指标。以特里尔社会应激测试(Trier Social Stress Test,TSST)及其变式作为应激源,以HPA轴的反应作为应激指标,影响个体在急性心理性应激情境中发生特异性神经内分泌反应的因素主要包括人口统计学、环境和应激频率三大方面,未来应加强急性心理性应激所诱发的神经内分泌反应的纵向研究。 Acute psychosocial stress is thought to induce neuroendocrine response by hypothalamus- pituitary-adrenal axis (HPAA) and sympathetic-adrenal medulla axis separately. Salivary cortisol is a stable indicator of HPAA activity response to acute psychosocial stress. This article focuses on studies which have employed the Trier Social Stress Test (TSST) or its modified version for stimulation of HPAA and discusses the role of various mediators (e.g., demographic factors, biological factors, and training) of the acute specificity stress response to psychosocial stress. Authors proposed that neuroendocrine responses to acute psvchosocial stress await longitudinal studies.
出处 《心理科学进展》 CSSCI CSCD 北大核心 2011年第9期1347-1354,共8页 Advances in Psychological Science
基金 中央高校基本科研业务费专项资金(SWU1009100) 西南大学211工程国家重点学科建设项目(NSKD11017)资助
关键词 急性心理性应激 特里尔社会应激测试 特异性神经内分泌反应 下丘脑一脑垂体一肾上腺轴 acute psychosocial stress Trier Social Stress Test (TSST) specificity neuroendocrine response hypothalamus-pituitary-adrenal axis (HPAA)
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