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急性冠状动脉综合征患者外周血单个核细胞基质金属蛋白酶-9活性水平的观察

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摘要 目的检测急性冠状动脉综合征（ACS）患者外周血单个核细胞基质金属蛋白酶-9（MMP-9）活性水平并探讨其意义。方法选取35例ACS患者和选10例经冠状动脉造影证实无冠状动脉病变患者（对照组），分离其外周血单个核细胞，酶谱法检测MMP-9活性。结果与对照组比较，ACS患者外周血单个核细胞基质金属蛋白酶-9活性显著增强（P〈0．01）。结论ACS患者循环中单个核细胞MMP-9活性显著增高，可能在不稳定斑块的发生和发展中起着重要作用。
作者 田橙 周志斌 张丽芬
机构地区 中国船舶重工集团公司职工医院内科 武汉科技大学附属天佑医院神经内科
出处 《临床内科杂志》 CAS 2011年第8期565-566,共2页 Journal of Clinical Internal Medicine
关键词 急性冠状动脉综合征 外周血单个核细胞 基质金属蛋白酶-9
分类号 R541 [医药卫生—心血管疾病]
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参考文献9

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临床内科杂志
2011年 第8期

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