子宫内膜和卵巢原发性双癌8例报道

Analysis about 8 Cases of Synchronous Primary Carcinomas of Endometrium and Ovary

目的探讨子宫内膜和卵巢原发性双癌的临床病理特点、治疗及预后。方法回顾性分析了2005年9月至2010年3月收治的子宫内膜和卵巢原发性双癌8例的病例资料。结果 8例患者平均年龄50岁,其中5例发生在绝经前。所有患者均接受手术治疗。术后有5例病理报告子宫内膜和卵巢同为子宫内膜样癌。8例患者术后均接受化疗。全部患者随访3～66个月,均存活,无复发。结论子宫内膜和卵巢原发性双癌较单纯子宫内膜癌或卵巢癌发病年龄早,以内膜和卵巢同为子宫内膜样癌为主要病理类型,首选手术治疗,术后再根据患者情况,辅以化疗,该病预后良好。

Objective To discuss the clinical pathologic features, treatment and prognosis of synchronous primary carcinomas of the endometrium and ovary. Methods 8 cases of synchronous primary carcinomas of endometrium and ovary, which lived in our hospital between March of 2005 and September of 2010, were analyzed retrospectively. Results The average age was 50 years in those cases. 5 cases were premenopausal women. All of the patients underwent operation. 5 cases had endometrioid carcinomas of both their endometrium and ovary in histology. 8 cases received adjuvant chemotherapy. The follow-up time was 3 to 66 months for all patients. All patients were alive with-out recurence. Conclusion A large series of women with synchronous primary carcinomas of the endometrium and ovary are younger than those only have one kind of cancer. The main pathological type is endometrial carcinoma of both the endometrium and ovary. Operation is the first option of the treatment. Adjuvant chemotherapy should be selected by pations＇ condition. Synchronous primary carcinomas appears to have a favorable prognosis.