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体外诱导的万古霉素耐药金黄色葡萄球菌耐药基因检测 被引量:1

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摘要 目的用PCR检测体外诱导的万古霉素耐药金黄色葡萄球菌(VRSA)的耐药基因vanA,探讨体外诱导VRSA对万古霉素耐药机制。方法用万古霉素体外诱导将1株异质性VRSA逐步诱导为VRSA;检测金黄色葡萄球菌特异性nuc基因和万古霉素耐药基因vanA。结果基因检测发现VRSA菌株均不含vanA基因。结论 VRSA不含vanA基因,故细胞壁增厚是导致金黄色葡萄球菌对万古霉素耐药的主要机制。
出处 《临床检验杂志》 CAS CSCD 北大核心 2011年第5期361-362,共2页 Chinese Journal of Clinical Laboratory Science
基金 安徽省高校青年教师资助项目(2006jql178)
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参考文献5

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