硫酸高铈催化合成苯甲醛1,2-丙二醇缩醛

Catalytic synthesis of benzaldehyde 1,2-propanediol acetalby ceric sulfate

以苯甲醛和1,2-丙二醇为原料,在硫酸高铈的催化下,合成了苯甲醛1,2-丙二醇缩醛,研究了物料配比、催化剂用量、反应时间等因素对产品收率的影响。实验表明,硫酸高铈是合成苯甲醛1,2-丙二醇缩醛的良好催化剂,在n(苯甲醛)∶n(1,2-丙二醇)=1∶1.5,催化剂用量为反应物料总质量的0.95%,带水剂环己烷10 mL,反应时间60 m in的条件下,苯甲醛1,2-丙二醇缩醛的收率可达91.10%。催化剂重复使用4次仍保持较高催化活性,产品经气相色谱定量分析,纯度>98.0%。

Benzaldehyde 1,2-propanediol acetal was synthesized from benzaldehyde and 1,2-propanediol under catalysis of eerie sulfate. The influence of ratio of aldehyde to alcohol, dosage of eatalyst and time on yield were investigated. The results showed that ceric sulfate exhibited excellent eatalytie activity. Under the conditions as follows ： molar ratio of benzaldehyde to 1,2-propanediol 1 ： 1.5, dosage of eatalyst 0.95 % of total mass of reactants, refluxing time 60 min, dosage of cyclohexane 10 mL, the yield of benzal dehyde 1,2-propanediol acetal is up to 91.10%. The catalyst can be reused for four times without significant yield declining. Purity of product analyzed by GC is over 98.0%.