吉西他滨联合顺铂致皮肤色素沉着1例分析

Analysis of 1 Case of Skin Pigmentation Induced by Gemcitabine Hydrochloride Injection Combined with Cisplatin

目的:提示临床重视注射用盐酸吉西他滨联合顺铂致皮肤色素沉着的不良反应。方法:报道注射用盐酸吉西他滨联合顺铂致罕见皮肤色素沉着1例,并搜集近年来国内、外医学文献,对本病例进行综合分析。结果与结论:注射用盐酸吉西他滨联合顺铂致色素沉着未见病例报道,有待于进一步观察研究。药源性皮肤色素沉着需引起足够重视,临床应加强对药源性皮肤色素沉着的了解,避免对患者身体和心理造成不良影响。

OBJECTIVE：To alert medical staff to pay attention to adverse drug reaction induced by gemcitabine hydrochloride combined with cisplatin,rare skin pigmentation.METHODS：1 case of rare skin pigmentation induced by gemcitabine hydrochloride combined with cisplatin was reported,and domestic and foreign medical literatures were collected to analyze the case report.RESULTS CONCLUSION：There was no report about skin pigmentation induced by gemcitabine hydrochloride combined with cisplatin.That was to be proven by further observation and research.Drug-induced skin pigmentation should be paid enough attention to and emphasized among clinicians and pharmacists so as to avoiding affect the physical and mental of patients.