阪崎肠杆菌致病性及致病机理研究进展

Advances in the study of the mechanisms of Cronobacter pathogenicity and pathogenesis

阪崎肠杆菌能够引起新生儿严重的脑膜炎、败血症和坏死性结肠炎,甚或遗留神经系统后遗症或导致死亡。研究表明阪崎肠杆菌致病机制可能与侵入、诱导凋亡及肠毒素作用有关。

Cronobacter spp.can cause severe neonatal meningitis,sepsis and necrotizing enterocolitis,lasting neurological sequelae,and even death.Research has shown that the mechanism of Cronobacter pathogenesis may be related to its invasion,induction of apoptosis,and toxicity to the intestines.