加味益胃汤用于小儿脾胃阴虚型厌食症的临床研究

Clinical observation on the effect of modified Yiweitang on anorexia of the Spleen andStomach Yin deficient type

目的观察加味益胃汤治疗小儿脾胃阴虚型厌食症的临床疗效。方法将90例脾胃阴虚型厌食症门诊患儿按1：1比例随机分为两组各45例，依据患儿年龄分别给予相应剂量的加味益胃汤煎液（治疗组）和儿宝颗粒（对照组），3次／d，连续治疗4周。观察两组患儿治疗前后的临床疗效，并进行比较。结果①症状积分：治疗组患儿治疗后的症状积分[呕吐（0．061±0．024）分、出汗（0．140±0．004）分、大便（0．024±0．011）分、小便（0．026±0．010）分]与对照组治疗后比较，差异有统计学意义（P〈0．05）。②临床疗效：治疗组总有效率为93．3％，对照组为91．1％，两组总有效率比较差异无统计学意义（X^2=0．886，P〉O．05）。③证候疗效：治疗组总有效率为95．6％，对照组为66．7％。两组证候的总有效率比较差异有统计学意义（X^2=0．625，P〈O．05）。结论加味益胃汤治疗小儿脾胃阴虚型厌食症疗效优于儿宝颗粒。

Objective To observe the curative effect of modified Yiweitang on anorexia of the Spleenand Stomach Yin deficient type. Methods 90 patients with anorexia belonging to spleen yln deficiency type were randomized in to 2 groups, by 1 ：1 ratio. According to the age of children, appropriate dose of modified Yiwei decoction （treatment group） and Erbao Granule （control group）, 3 times/d, for 4 weeks were given to the children, Clinical efficacy of the treatment group was observed before and after the treatment and compared with the control group. Results ① symptom scores： Vomiting （0.061±0.024）, sweating （0.140±0.004）, stool （0.024±0.011）, urine （0.026 ±0.010） in treatment group after treatment, showing statistical significance （P〈 0.05） with the control group. ②disease treatment： The total effective rate was 93.3% and 91.1% in the treatment group and the control group, the difference was not statistically significant （X^2=0.886, P〉0.05）. ③ symptoms treatment： The total effective rate was 95.6% and 66.7%0 in the treatment group and the control group respectively, the difference was statistically significant （X^2=0.625, P〈0.05）. Conclusion The treatment of modified Yiweitang was better than Erbao Granule in treating children with anorexia belonging to stomach yin deficiency.