小儿轮状病毒肠炎伴良性惊厥12例临床分析

Clinical Study on 12 Cases of Rotavirus Gastroenteritis with Benign Convulsions in Children

目的分析小儿轮状病毒肠炎合并良性惊厥的临床特点,探讨其可能的病因,提高对本病的认识。方法对2008年1月-2010年1月儿科确诊的12例轮状病毒肠炎合并良性惊厥患儿的临床资料及实验室检查结果进行回顾性分析。结果 12例中年龄最小6个月、最大28个月,冬季多发,惊厥发生于病程的第1～3天,在1次病程中可单次或多次发作,惊厥发作形式为全身强直-阵挛性发作、历时均不超过5 m in,惊厥控制后未予抗癫癎治疗,随访1～2年未有复发。结论轮状病毒肠炎可以伴有良性惊厥,1～2岁高发,惊厥易控制,无需长期抗癫癎治疗,预后好。

Objective To study the clinical features of the rotavirus gastroenteritis with benign convulsions in children and explore its possible etiology,and improve the understanding of this disease.Methods Twelve infants with the rotavirus gastroenteritis and benign convulsions in our hospital from January 2008 to January 2010 were observed and followed up,and their clinical and investigational material were analyzed respectively.Results The ages of onset in 12 cases ranged from 6 to 28 months old.The episodes frequently occurred in winter.The seizure occurred in first 3 days of an episode.During an episode the numbers of seizure was single or cluster.The pattern of seizure was generalization in 100%,with short lasting time,less than 5 minutes.No antiepileptic treatment was given to all as the seizures stopped.The follow-up of 1 year to 2 years showed no relapse case.Conclusion Rotavirus gastroenteritis can be accompanied by the benign convulsions,the prevailing age is 1 to 2 years,convulsions can be controlled easily,long-term antiepileptic treatment may not be necessary,and the prognosis of the patients is good.