不同温度的甘露醇对静脉刺激性的临床观察

The Clinical Observation of Different Temperature Mannitol for Vein Irritant

目的探讨输入不同温度的甘露醇对局部血管刺激性的影响。方法比较输注36℃的20%甘露醇与室温(17～22℃)的20%甘露醇对患者局部血管的影响;首先采用分组对照法,将120例患者随机分为实验组与对照组各60例,比较两组患者疼痛程度和静脉炎发生率;再采用自身对照法,选择34例患者,共输注甘露醇343例次,观察组输注36℃甘露醇177例次,对照组输注室温甘露醇166例次,再次比较患者2种温度疼痛程度和静脉炎发生率。结果实验组疼痛程度明显轻于对照组(P<0.01),静脉炎发生率也低于对照组(P<0.05)。结论输注36℃的20%甘露醇比输入常温的20%甘露醇所致的疼痛轻、静脉炎的发生率低。

Objective To investigate at impact of different temperatures infusion of mannitol on the local vascular irritation.Methods The influence of 20 percent of infusion（36℃） mannitol and 20 percent of room temperature（17-22℃） mannitol on partial blood vessel were compared.120 patients were divided into the experimental group and control group with 60 examples each group.Ache degree and incidence rate of phlebitis between 2 groups were compared.34 patients were chosen and infused mannitol 343 times,with infusing 36 ℃ mannitol 177 times in experimental group,and infusing room temperature mannitol 166 times in control group.Ache degree and incidence rate of phlebitis between 2 groups were also compared.Results The ache degree of experimental group was lighter than that of observation group（P0.01）,incidence rate of phlebitis in experimental group was lower than that in observation group（P0.05）.Conclusion Infusing of 20 percent of 36 ℃ mannitol was lighter than the infusing of 20 percent of normal temperature mannitol,and incidence rate of phlebitis was lower.