改良ARROW导管引流联合5-氟尿嘧啶、高聚生灌注治疗恶性腹腔积液

The Therapeutic Effect of Malignant Ascites with Improved Central Venous Catheter Combined with 5-Fluorouracil and Highly Agglutinative Staphylococcin

目的探讨改良中心静脉导管置管引流系统(ARROW导管)引流联合5-氟尿嘧啶、高聚生灌注治疗恶性腹腔积液的疗效及安全性。方法对26例恶性腹腔积液患者留置经过改良的ARROW导管,待积液放尽,在腹腔中灌注5-氟尿嘧啶及高聚生。结果 26例患者中CR 5例,PR 18例,SD 3例,有效率为88.5%。毒副反应患者能耐受。结论改良的ARROW导管引流联合5-氟尿嘧啶、高聚生灌注治疗恶性腹腔积液疗效好、创伤小、毒副反应轻。

Objective To investigate the therapeutic effect and security of improved central venous catheter combined with 5-fluorouracil and highly agglutinative staphylococcin in the treatment of malignant ascites.Methods Twenty six patients with malignant ascites were detained by improved central venous catheter and injected by 5-fluorouracil and highly agglutinative staphylococcin in their peritoneal cavity.Results The 5 patients were complete remission,the 18 patients partial remission,and the 3 patients stabilized.The effective rate was 88.5%.The toxicities were mild and tolerated.Conclusion The treatment of malignant ascites with improved central venous catheter combined with 5-fluorouracil and highly agglutinative staphylococcin is effective and safe.